Merck

 

Merck, a leading science and technology company, operates across healthcare, life science and performance materials. Around 57,000 employees work to make a positive difference to millions of people's lives every day by creating more joyful and sustainable ways to live. From advancing gene editing technologies and discovering unique ways to treat the most challenging diseases to enabling the intelligence of devices – the company is everywhere. In 2019, Merck generated sales of € 16.2 billion in 66 countries.
 
Scientific exploration and responsible entrepreneurship have been key to Merck's technological and scientific advances. This is how Merck has thrived since its founding in 1668. The founding family remains the majority owner of the publicly listed company. Merck holds the global rights to the Merck name and brand. The only exceptions are the United States and Canada, where the business sectors of Merck operate as EMD Serono in healthcare, MilliporeSigma in life science, and EMD Performance Materials.
 

Contact us

Merck KGaA
Frankfurter Str. 250
Postcode: MA014/902
64293 Darmstadt
Germany

For more information please contact isosales@milliporesigma.com
Or visit our website https://wwwpws.sigmaaldrich.com/DE/en
 
Mandatory information can be found at http://mandatories.merckgroup.com
 

Bio NMR

 

Structural determination by NMR is an important tool for understanding protein form and function. 13C, 15N, D labeled carbohydrates and amino acids as part of the expression system allows for targeted protein site studies. Or, if efficiency gains are needed, consider the benefits of ISOGRO® isotopically-labeled media.

Hyperpolarization

 

The use of stable isotope labeled metabolites to render visible metabolic images of the body offers insight into metabolism of both disease and healthy tissues. ISOTEC® is committed to
offering an extensive array of labeled compounds for this purpose, many available from our GMP facility.


Link:
https://www.sigmaaldrich.com/DE/en/products/chemistry-and-biochemicals/stable-isotopes
 

Phosphoramidites


Enhanced molecular biology research by using selectively-labeled RNA phosphoramidites to synthesize labeled oligonucleotides. Labeled probes allow for site-specific interrogation.

Link:
https://www.sigmaaldrich.com/DE/en/search/phosphoramidites?facet=facet_product_category%3Astable%20isotopes&focus=products&page=1&perPage=30&sort=relevance&term=phosphoramidites&type=product

Methyl labeling kits


Methyl groups are ideal probes for studying protein structure and function by NMR. Comprehensive easy to use kits lead to isotopic labeling of a variety of amino acid residues.

Link:
https://www.sigmaaldrich.com/DE/en/technical-documents/technical-article/chemistry-and-synthesis/peptide-synthesis/methyl-isotope-labeling

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